According to the definition adopted by the World Health Organisation the probiotics are “Live microorganisms which when administered in adequate amounts conferring a health benefit on the host”. Prebiotics are non-digestible substances that when consumed provide a beneficial physiological effect on the host by selectively stimulating the favorable growth or activity of a limited number of indigenous bacteria. Synbiotics refer to nutritional supplements combining probiotics and prebiotics in a form of synergism, hence synbiotics.
ProbioFlor® is based on a low lactose freeze-dried fermented milk product of high biological value with combined probiotic and prebiotic effect. ProbioFlor® contains high concentrations of biologically important substances, either originating from milk or supplemented additionally: pectin (tablets only), inulin, oligopeptides and dipeptides, free amino acids, lactic acid, short-chain fatty acids, polyunsaturated fatty acids, glucose, galactose, fructose, vitamins, bacteriocins, exopolysaccharides, minerals and trace elements, etc. Due to its reduced lactose content ProbioFlor® is particularly recommendable for persons suffering from lactose intolerance.
The lactic acid bacteria are famous for their role as major biological regulators of the gastrointestinal tract and antagonistic effect against pathogenic microorganisms. They neutralise food mutagens produced in colon, alleviate allergic reactions, and lower serum cholesterol. Consumption of probiotics containing yoghurt bacteria L. bulgaricus and S. thermophilus can reduce the incidence and severity of antibiotic-associated diarrhoea. Strains of Lactobacillus bulgaricus exhibit profound immunostimulatory and immunomodulatory effects, activate the gut mucosal immunity, induce cytokine response, and reduce the risk of allergic diseases. Recently, a cytoprotective agent produced L. bulgaricus, which might contribute to its well known antiproliferative, antimutagenic and anticarcinogenic activity was discovered. Additionally, L. bulgaricus cultures can provide a source of dietary antioxidants.
The bacterial strains included in ProbioFlor® are selected according to their beneficial influence on the human health. ProbioFlor® strains which are able to survive within the human gastrointestinal tract and exhibit strong antimicrobial activity against extraintestinal and intestinal pathogenic bacteria. Clinical studies using ProbioFlor® capsules demonstrate that ProbioFlor® is well tolerated and contributes to the regulation of the intestinal bacterial ecosystem. The intake of ProbioFlor® synbiotic was effective in constipation, functional dyspepsia and food intolerance. Results from clinical trials indicate that ProbioFlor® exhibits profound immunostimulatory effect in the human oral cavity. The reception of chewable ProbioFlor® tablets resulted in increased secretion of IgA in the human saliva, which might have a highly protective influence on the human health due to improvement of the local immune defense, thus preventing infections in the lower respiratory tract.
The microbial strains included in ProbioFlor® as well as in any other product of Rm and Biomed Ltd. comprise only of bacteria which are not genetically modified, isolated from ecologically preserved natural sources.
The macufacturer is a member of the European Food and Feed Culture Association and the EU-funded Lactic Acid Bacteria Industrial Platform.
Specifications-characteristics-indications of the product
- A Swiss formula vegetarian safe with no side effects
- 500 million CFU per tablet
- 30 chewable tablets with natural caramel taste
- Optimizes your immune and digestive system
- Patented blend includes 3 unique strains of Lactobacillus bulgaricus
- Formulated for fast reproduction of the GI system
- Isolated from plants and natural resources in highly protected ecological areas
- Inulin prebiotic from green plants aids the growth of the ‘good bacteria’ in the GI system
- Support your body’s immune system
- Promote correct digestion and absorption of food nutrients
- Help regulate normal blood cholesterol levels
- Help relieve lactose introlerance
- Help fight stress related conditions
- Prevent constipation, bloating, diarrhea, and flatulence
- Overcome skin problems
Gibson GR, Roberfroid MB. Dietary modulation of the human colonic microbiota: introducing the concept of prebiotics. J. Nutr. 1995. Jun;125(6):1401-12.
Ljungh, A and Wadström, T. Lactic Acid Bacteria as Probiotics. Curr. Issues Intestinal Microbiol. 2006. 7: 73–90.
Tannock, GW. Probiotics and prebiotics. Where are we going? Norfolk, UK: Caister Acad Press 2002.
Hickson M, D’Souza AL, Muthu N, Rogers TR, Want S, Rajkumar C, and Bulpitt CJ. Use of probiotic Lactobacillus preparation to prevent diarrhoea associated with antibiotics: randomised double blind placebo controlled trial. BMJ. 2007. 14;335(7610):80.
Isolauri, E. Probiotics: Effects on Immunity, Am. J. Clin. Nutr. 2001. 73: 444S-450S.
Galdeano CM, and Perdigón G. Role of viability of probiotic strains in their persistence in the gut and in mucosal immune stimulation. J. Appl. Microbiol. 2004. 97(4):673-81.
Johns P, Pereira SL, Leonard AE, Mukerji P, Shalwitz RA, Dowlati L, Phillips RR, Bergana MS, Holton JD, and Das T. Cytoprotective agent in Lactobacillus bulgaricus extracts. Curr. Microbiol. 2007. 54(2):131-5.
Pessi T, Sütas Y, Saxelin M, Kallioinen H, and Isolauri E. Antiproliferative effects of homogenates derived from five strains of candidate probiotic bacteria. Appl. Environ. Microbiol. 1999. 65(11):4725-8.
Wollowski I, Rechkemmer G, Pool-Zobel BL. Protective role of probiotics and prebiotics in colon cancer.Am. J. Clin. Nutr. 2001. 73(2 Suppl):451S-455S.
Lin MY, and Yen CL. Antioxidative ability of lactic acid bacteria. J. Agric. Food. Chem. 1999. 47(4):1460-6.
Saide JA, and Gilliland SE. Antioxidative activity of lactobacilli measured by oxygen radical absorbance capacity. J. Dairy Sci. 2005. 88(4):1352-7.